Bevacizumab and irinotecan in recurrent malignant glioma, a single institution experience

Bevacizumab and irinotecan in recurrent malignant glioma, a single institution experience

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Background.Treatment options of recurrent malignant gliomas are very limited and with a kramer tiger guitar poor survival benefit.The results from phase II trials suggest that the combination of bevacizumab and irinotecan is beneficial.Patients and methods.The medical documentation of 19 adult patients with recurrent malignant gliomas was retrospectively reviewed.

All patients received bevacizumab (10 mg/kg) and irinotecan (340 mg/m2 or 125 mg/m2) every elbeco adu ripstop pants two weeks.Patient clinical characteristics, drug toxicities, response rate, progression free survival (PFS) and overall survival (OS) were evaluated.